|
|
undecaprenol + ATP <=> H+ + undecaprenyl_phosphate + ADP
|
2.7.1.66
undecaprenol kinase
|
–
|
| |
BRENDA:
BR47793
KEGG:
R05626
MetaCyc:
UNDECAPRENOL-KINASE-RXN
SABIO-RK:
5224
|
|
|
|
UDP-MurNAc-pentapeptide + undecaprenyl_phosphate <=> Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UMP
|
2.7.8.13
phospho-N-acetylmuramoyl-pentapeptide-transferase
|
–
|
| |
BRENDA:
BR48088
KEGG:
R05629
MetaCyc:
RXN-8975
SABIO-RK:
5227
|
|
|
|
UDP-MurNAc-L-Ala-D-Glu + L-lysine + ATP <=> H+ + phosphate + UDP-MurNAc-Ala-D-Glu-Lys + ADP
|
6.3.2.7
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase
|
–
|
| |
BRENDA:
BR123;
BS427396
KEGG:
R02786
MetaCyc:
6.3.2.7-RXN
|
|
|
|
UDP-MurNAc-Ala-D-Glu-Lys + D-Ala-D-Ala + ATP <=> H+ + UDP-MurNAc-pentapeptide + phosphate + ADP
|
6.3.2.10
UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
6.3.2.4
D-alanine---D-alanine ligase
|
–
–
|
| |
BRENDA:
BR102
KEGG:
R04573
MetaCyc:
6.3.2.10-RXN
SABIO-RK:
4244
|
|
|
|
2 Glycyl-tRNA(Gly) + N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-triglycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine <=> 2 tRNAMet + N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-pentaglycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine
|
2.3.2.18
N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase
|
–
|
| |
KEGG:
R08778
|
|
|
|
D-alanine + ATP <=> H+ + D-Ala-D-Ala + phosphate + ADP
|
6.1.2.1
D-alanine---(R)-lactate ligase
6.3.2.35
D-alanine---D-serine ligase
6.3.2.4
D-alanine---D-alanine ligase
|
–
–
–
|
| |
BRENDA:
BR120
KEGG:
R01150
MetaCyc:
DALADALALIG-RXN
SABIO-RK:
1391
|
|
|
|
undecaprenyl_diphosphate + H2O <=> H+ + undecaprenyl_phosphate + phosphate
|
3.1.3.27
phosphatidylglycerophosphatase
3.6.1.27
undecaprenyl-diphosphate phosphatase
|
–
–
|
| |
BRENDA:
BR22817
KEGG:
R05627
MetaCyc:
UNDECAPRENYL-DIPHOSPHATASE-RXN
SABIO-RK:
5225
|
|
|
|
UDP-N-acetylmuramate + NAD+ <=> UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADH + H+
|
1.3.1.98
UDP-N-acetylmuramate dehydrogenase
|
–
|
| |
KEGG:
R03191
|
|
|
|
ATP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + NH3 <=> ADP + phosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
|
6.3.5.13
lipid II isoglutaminyl synthase (glutamine-hydrolysing)
|
–
|
| |
KEGG:
R05030
|
|
|
|
UDP-N-acetyl-D-glucosamine + phosphoenolpyruvate <=> UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + phosphate
|
2.5.1.7
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
|
–
|
| |
BRENDA:
BR47474
KEGG:
R00660
MetaCyc:
UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN
SABIO-RK:
1042
|
|
|
|
UDP-N-acetylmuramoyl-L-Ala + D-glutamate + ATP <=> UDP-MurNAc-L-Ala-D-Glu + phosphate + ADP + H+
|
6.3.2.9
UDP-N-acetylmuramoyl-L-alanine---D-glutamate ligase
|
–
|
| |
BRENDA:
BR125;
BS416658
KEGG:
R02783
MetaCyc:
UDP-NACMURALA-GLU-LIG-RXN
SABIO-RK:
2659
|
|
|
|
UDP-N-acetylmuramoyl-pentapeptide + undecaprenyl_phosphate <=> lipid_I + UMP
|
2.7.8.13
phospho-N-acetylmuramoyl-pentapeptide-transferase
|
–
|
| |
BRENDA:
BS402203
KEGG:
R05630
MetaCyc:
PHOSNACMURPENTATRANS-RXN
|
|
|
|
L-alanyl-tRNA + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl)-D-alanyl-D-alanine <=> tRNAMet + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl-L-alanyl)-D-alanyl-D-alanine
|
2.3.2
|
–
|
| |
KEGG:
R08780
|
|
|
|
L-alanine + UDP-N-acetylmuramate + ATP <=> H+ + UDP-N-acetylmuramoyl-L-Ala + phosphate + ADP
|
6.3.2.8
UDP-N-acetylmuramate---L-alanine ligase
6.3.2.B2
|
–
–
|
| |
BRENDA:
BR124
KEGG:
R03193
MetaCyc:
UDP-NACMUR-ALA-LIG-RXN
|
|
|
|
UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate + D-Ala-D-Ala + ATP <=> H+ + UDP-N-acetylmuramoyl-pentapeptide + phosphate + ADP
|
6.3.2.10
UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
|
–
|
| |
KEGG:
R04617
MetaCyc:
UDP-NACMURALGLDAPAALIG-RXN
SABIO-RK:
4284
|
|
|
|
(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> undecaprenyl_diphosphate + diphosphate
|
2.5.1.31
ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
2.5.1.M1
|
–
–
|
| |
BRENDA:
BR47468
KEGG:
R06447
MetaCyc:
RXN-8999;
RXN-9138
SABIO-RK:
12133
|
|
|
|
Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine <=> H+ + lipid_II + UDP
|
2.4.1.227
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
|
–
|
| |
BRENDA:
BR44201
KEGG:
R05662;
R06173
MetaCyc:
RXN-8976
|
|
|
|
UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate + ATP <=> H+ + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate + phosphate + ADP
|
6.3.2.13
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate ligase
|
–
|
| |
BRENDA:
BR105;
BS369028
KEGG:
R02788
MetaCyc:
UDP-NACMURALGLDAPLIG-RXN
|
|
|
|
L-alanyl-tRNA + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol <=> tRNAMet + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl)-D-alanyl-D-alanine
|
2.3.2.10
UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase
|
–
|
| |
KEGG:
R08779
|
|
|
|
NADP+ + UDP-N-acetylmuramate <=> H+ + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine
|
1.3.1.98
UDP-N-acetylmuramate dehydrogenase
|
–
|
| |
BRENDA:
BR29223
KEGG:
R03192
MetaCyc:
UDPNACETYLMURAMATEDEHYDROG-RXN
SABIO-RK:
3021
|
|
|
|
Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine <=> tRNAMet + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)-D-alanyl-D-alanine
|
2.3.2.16
lipid II:glycine glycyltransferase
|
–
|
| |
KEGG:
R08776
|
|
|
|
2 Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)-D-alanyl-D-alanine <=> 2 tRNAMet + N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-triglycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine
|
2.3.2.17
N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase
|
–
|
| |
KEGG:
R08777
|
|
|
|
lipid_I + UDP-N-acetyl-D-glucosamine <=> H+ + lipid_II + UDP
|
2.4.1.227
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
|
–
|
| |
BRENDA:
BS378301
KEGG:
R05032;
R06174
MetaCyc:
NACGLCTRANS-RXN
|
|
